Evidences for Local Allergic Rhinitis

Jang, Tae Young; Kim, Young Hyo

doi:2016.23.1.1

J Rhinol > Volume 23(1); 2016

Review

Journal of Rhinology 2016;23(1):1-5.
Published online May 31, 2016.
DOI: https://doi.org/10.18787/jr.2016.23.1.1

Evidences for Local Allergic Rhinitis

Tae Young Jang, Young Hyo Kim

Department of Otorhinolaryngology, Head and Neck Surgery, Inha University College of Medicine, Incheon, Korea. inhaorl@inha.ac.kr

국소 알레르기 비염의 최신지견

장태영김영효,

인하대학교 의과대학 이비인후과학교실

Abstract

Local allergic rhinitis is defined as a localized allergic reaction of the nasal mucosa in the absence of systemic atopy. Its main pathophysiological mechanism can be summarized as: 1) increased specific immunoglobulin E in the nasal fluid, and 2) Th2 allergic mechanism localized in the nasal mucosa. In patients whose result of a skin prick test is totally negative for all antigens, practitioners could diagnose local allergic rhinitis using a nasal provocation test. Oral antihistamines and intranasal steroids can be an effective treatment. Subcutaneous immunotherapy can also be helpful. Further study is essential to further elucidate the detailed pathophysiologic mechanism and set up global standard diagnostic criteria.

Key Words: Vasomotor rhinitis;Allergic rhinitis;Immunoglobulin E;Nasal provocation tests