A case of huge extramedullary plasmacytoma arising from both nasal cavity

Kim, Young Hyo; Kim, Jae Eun; Jang, Tae Young

Case Report

Journal of Rhinology 2012;19(2):123-126.
Published online November 30, 2012.

A case of huge extramedullary plasmacytoma arising from both nasal cavity

Young Hyo Kim, Jae Eun Kim, Tae Young Jang

Department of Otorhinolaryngology-Head and Neck Surgery, INHA University College of Medicine, Incheon, Korea. jangty@inha.ac.kr

양측 비강에 다발성으로 발생한 거대 골수외 형질세포종 1예

김영효, 김재은, 장태영

인하대학교 의학전문대학원 이비인후-두경부외과학교실

Abstract

A 52-year-old patients suffering from nasal stuffiness had necrotic, ulcerative polypoid mass in both nasal cavity. CT and MRI revealed bilateral polypoid mass with bony invasion in left maxillary anterior and posterior wall, left pterygopalatine fossa and right central skull base. The patient was diagnosed as plasmacytoma by histologic examination. To rule out multiple myeloma, several additive studies such as bone scan, bone marrow biopsy, urine Bence-Jons protein, serum protein electrophoresis, peripheral blood smear were performed and all results were negative. The patient was transferred to department of hemato-oncology and got 2 times of chemotherapy consisting of cyclophosphamide and dexamethasone and radiotherapy (5400 cGy / 30 fractionation). A month after the completion of chemoradiotherapy, the sized of mass decreased significantly without evidence of progression.

Key Words: Plasmacytoma;Multiple myeloma;Polyp